Social Isolation is Associated With Altered Neural Reactivity to the Sight of Food Summary A study published in JAMA Network Open examined how perceived social isolation affects the brain’s response to food and related eating behaviors in women. Researchers found that women who felt more socially isolated showed altered neural activity when viewing pictures of food , particularly in brain networks involved in appetite, motivation, decision-making, and attention (default mode, executive control, and visual attention networks). The study included 93 women aged 18–50 . Participants completed assessments of loneliness, diet quality, eating behaviors, food cravings, food addiction , resilience, and mental health . They also underwent fMRI scans while viewing images of sweet, savory, healthy, and unhealthy foods. Key findings showed that women with high perceived loneliness: Had higher body fat percentages Consumed lower-quality diets Reported more emotional and reward-driven e...